Gene Expression Regulation

Multi-omics analysis in primary T cells elucidates mechanisms behind disease-associated genetic loci
BACKGROUND: Genome-wide association studies (GWAS) have uncovered the genetic basis behind many diseases and conditions. However, most …
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HOX paralogs selectively convert binding of ubiquitous transcription factors into tissue-specific patterns of enhancer activation
Gene expression programs determine cell fate in embryonic development and their dysregulation results in disease. Transcription factors …
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OscoNet: inferring oscillatory gene networks
BACKGROUND: Oscillatory genes, with periodic expression at the mRNA and/or protein level, have been shown to play a pivotal role in …
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