Humans

Multi-omics analysis in primary T cells elucidates mechanisms behind disease-associated genetic loci
BACKGROUND: Genome-wide association studies (GWAS) have uncovered the genetic basis behind many diseases and conditions. However, most …
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Identification of differences in CD4+ T-cell gene expression between people with asthma and healthy controls
Functional enrichment analysis of genome-wide association study (GWAS)-summary statistics has suggested that CD4+ T-cells play an …
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Sex differences in innate anti-viral immune responses to respiratory viruses and in their clinical outcomes in a birth cohort study
The mechanisms explaining excess morbidity and mortality in respiratory infections among males are poorly understood. Innate immune …
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Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits
Chromatin looping between regulatory elements and gene promoters presents a potential mechanism whereby disease risk variants affect …
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OscoNet: inferring oscillatory gene networks
BACKGROUND: Oscillatory genes, with periodic expression at the mRNA and/or protein level, have been shown to play a pivotal role in …
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